Peyronie's Disease

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Signs and Symptoms

Peyronie's disease may be mild or severe, and may develop rapidly or over time. Symptoms include the following:

• Hardened tissue (plaque) in the penis
  
• Pain during erection
  
• Curve in the penis during erection
  
• Distortion of the penis (e.g., indentation, shortening)
  

Plaque usually develops on the top of the shaft, causing the penis to bend upward during erection, but it may occur on the bottom, causing a downward bend. If plaque develops on the top and the bottom, indentations and shortening may occur. In about 13% of cases, plaque does not cause severe pain or curvature, and the condition resolves on its own.

In severe cases, pain and curvature result in erectile dysfunction (impotence). If there are several areas of plaque, incomplete erection may occur.

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